Metformin Inhibits Angiotensin II-Induced Differentiation of Cardiac Fibroblasts into Myofibroblasts

Differentiation of cardiac fibroblasts into myofibroblasts is a critical event in the progression of cardiac fibrosis that leads to pathological cardiac remodeling. Metformin, an antidiabetic agent, exhibits a number of cardioprotective properties. However, much less is known regarding the effect of...

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Main Authors: Bai, Jian, Zhang, Na, Hua, Ying, Wang, Bingjian, Ling, Lin, Ferro, Albert, Xu, Biao
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759374/
https://ncbi.nlm.nih.gov/pubmed/24023727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072120
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