In Vitro Effects of Pirfenidone on Cardiac Fibroblasts: Proliferation, Myofibroblast Differentiation, Migration and Cytokine Secretion

Cardiac fibroblasts (CFs) are the primary cell type responsible for cardiac fibrosis during pathological myocardial remodeling. Several studies have illustrated that pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone) attenuates cardiac fibrosis in different animal models. However, the effects of pirfen...

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Main Authors: Shi, Qiang, Liu, Xiaoyan, Bai, Yuanyuan, Cui, Chuanjue, Li, Jun, Li, Yishi, Hu, Shengshou, Wei, Yingjie
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223242/
https://ncbi.nlm.nih.gov/pubmed/22132230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028134
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