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Caveolae Regulation of Mechanosensitive Channel Function in Myotubes

Mutations that lead to muscular dystrophy often create deficiencies in cytoskeletal support of the muscle sarcolemma causing hyperactive mechanosensitive cation channel (MSC) activity and elevated intracellular Ca(2+). Caveolae are cholesterol-rich microdomains that form mechanically deformable inva...

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Autores principales: Huang, Haixia, Bae, Chilman, Sachs, Frederick, Suchyna, Thomas M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758351/
https://ncbi.nlm.nih.gov/pubmed/24023653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072894
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