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Human PIEZO1 Ion Channel Functions as a Split Protein

PIEZO1 is a mechanosensitive eukaryotic cation-selective channel that rapidly inactivates in a voltage-dependent manner. We previously showed that a fluorescent protein could be encoded within the hPIEZO1 sequence without loss of function. In this work, we split the channel into two at this site and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bae, Chilman, Suchyna, Thomas M., Ziegler, Lynn, Sachs, Frederick, Gottlieb, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786117/
https://ncbi.nlm.nih.gov/pubmed/26963637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151289
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