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Human PIEZO1: Removing Inactivation

PIEZO1 is an inactivating eukaryotic cation-selective mechanosensitive ion channel. Two sites have been located in the channel that when individually mutated lead to xerocytotic anemia by slowing inactivation. By introducing mutations at two sites, one associated with xerocytosis and the other artif...

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Detalhes bibliográficos
Main Authors: Bae, Chilman, Gottlieb, Philip A., Sachs, Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752115/
https://ncbi.nlm.nih.gov/pubmed/23972840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.019
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