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Modeling Ion Channels in the Gigaseal

The ability to form gigaseals is essential for patch-clamp electrophysiology; however, ion channels located in the seal can produce measureable currents. To explore the expected properties of channels in the seal (i.e., rim channels), we created a mathematical model. The seal was a two-dimensional c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bae, Chilman, Markin, Vladislav, Suchyna, Thomas, Sachs, Frederick
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297810/
https://ncbi.nlm.nih.gov/pubmed/22261052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.11.002
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