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Caveolae Regulation of Mechanosensitive Channel Function in Myotubes

Mutations that lead to muscular dystrophy often create deficiencies in cytoskeletal support of the muscle sarcolemma causing hyperactive mechanosensitive cation channel (MSC) activity and elevated intracellular Ca(2+). Caveolae are cholesterol-rich microdomains that form mechanically deformable inva...

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Detalhes bibliográficos
Main Authors: Huang, Haixia, Bae, Chilman, Sachs, Frederick, Suchyna, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758351/
https://ncbi.nlm.nih.gov/pubmed/24023653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072894
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