FTY720-Induced Human Pulmonary Endothelial Barrier Enhancement is Mediated by c-Abl

BACKGROUND: Strategies to improve pulmonary endothelial barrier function are needed to reverse the devastating effects of vascular leak in acute respiratory distress syndrome (ARDS). FTY720 is a pharmaceutical analogue of the potent barrier-enhancing phospholipid, sphingosine 1-phosphate (S1P). FTY7...

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Bibliographic Details
Main Authors: Wang, Lichun, Chiang, Eddie T., Simmons, John T., Garcia, Joe G.N., Dudek, Steven M.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758235/
https://ncbi.nlm.nih.gov/pubmed/21071472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00047810
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