Suberoylanilide hydroxamic acid (SAHA) inhibits EGF-induced cell transformation via reduction of cyclin D1 mRNA stability

Suberoylanilide hydroxamic acid (SAHA) inhibiting cancer cell growth has been associated with its down-regulation of cyclin D1 protein expression at transcription level or translation level. Here, we have demonstrated that SAHA inhibited EGF-induced Cl41 cell transformation via the decrease of cycli...

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Autores principales: Zhang, Jingjie, Ouyang, Weiming, Li, Jingxia, Zhang, Dongyun, Yu, Yonghui, Wang, York, Li, Xuejun, Huang, Chuanshu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758130/
https://ncbi.nlm.nih.gov/pubmed/22749963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.06.012
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