Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance()

JS-K is a nitric oxide (NO)-releasing prodrug of the O(2)-arylated diazeniumdiolate family that has demonstrated pronounced cytotoxicity and antitumor properties in a variety of cancer models both in vitro and in vivo. The current study of the metabolic actions of JS-K was undertaken to investigate...

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Bibliografiska uppgifter
Huvudupphovsmän: Maciag, Anna E., Holland, Ryan J., Robert Cheng, Y.-S., Rodriguez, Luis G., Saavedra, Joseph E., Anderson, Lucy M., Keefer, Larry K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2013
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757670/
https://ncbi.nlm.nih.gov/pubmed/24024144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2012.12.002
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