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Triple Helical Recognition of Pyrimidine Inversions in Polypurine Tracts of RNA by Nucleobase-modified PNA

Peptide nucleic acids containing 2-pyrimidinone (P) and 3-oxo-2,3-dihydropyridazine (E) heterocycles recognized C-G and U-A inversions in a polypurine tract of double helical RNA with high affinity and sequence selectivity at pH 6.25. E-modified PNA bound strongly to bacterial A-site RNA, while no b...

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Bibliografski detalji
Glavni autori: Gupta, Pankaj, Zengeya, Thomas, Rozners, Eriks
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757498/
https://ncbi.nlm.nih.gov/pubmed/21909545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc14706d
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