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Short Peptide Nucleic Acids Bind Strongly to Homopurine Tract of Double Helical RNA at pH 5.5

The important role that non-coding RNA plays in cell biology makes it an attractive target for molecular recognition. However, the discovery of small molecules that bind double helical RNA selectively and may serve as biochemical probes and potential drug leads has been relatively slow. Herein, we s...

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Main Authors: Li, Ming, Zengeya, Thomas, Rozners, Eriks
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929816/
https://ncbi.nlm.nih.gov/pubmed/20527745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101384k
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