Triple Helical Recognition of RNA Using 2-Aminopyridine-Modified PNA at Physiologically Relevant Conditions

Peptide nucleic acids containing thymidine and 2-aminopyridine (M) nucleobases formed stable and sequence selective triple helices with double stranded RNA at physiologically relevant conditions. The M-modified PNA displayed unique RNA selectivity by having two orders of magnitude higher affinity fo...

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Hlavní autoři: Zengeya, Thomas, Gupta, Pankaj, Rozners, Eriks
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756501/
https://ncbi.nlm.nih.gov/pubmed/23125029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201207925
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