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The DNA damage checkpoint protein RAD9A is essential for male meiosis in the mouse

In mitotic cells, RAD9A functions in repairing DNA double-strand breaks (DSBs) by homologous recombination and facilitates the process by cell cycle checkpoint control in response to DNA damage. DSBs occur naturally in the germline during meiosis but whether RAD9A participates in repairing such brea...

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Détails bibliographiques
Auteurs principaux: Vasileva, Ana, Hopkins, Kevin M., Wang, Xiangyuan, Weisbach, Melissa M., Friedman, Richard A., Wolgemuth, Debra J., Lieberman, Howard B.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757332/
https://ncbi.nlm.nih.gov/pubmed/23788429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.126763
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