Wordt geladen...
FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development
FBXW7 is the substrate recognition component of a SCF-type E3 ubiquitin ligase. It has multiple targets such as Notch1, c-Jun, and cyclin E that function in critical developmental and signalling pathways. Mutations in FBXW7 are often found in many types of cancer. In most cases, these mutations do n...
Bewaard in:
| Hoofdauteurs: | , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley & Sons, Ltd.
2011
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757315/ https://ncbi.nlm.nih.gov/pubmed/21503901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2874 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|