Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Signaling Regulates Mitochondrial Biogenesis and Respiration via Estrogen-related Receptor α (ERRα)

Mitochondrial abnormalities are associated with cancer development, yet how oncogenic signals affect mitochondrial functions has not been fully understood. In this study, we investigate the relationship between mitochondrial alterations and PI3K/protein kinase B (AKT) signaling activation using hepa...

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Bibliographic Details
Main Authors: Li, Yang, He, Lina, Zeng, Ni, Sahu, Divya, Cadenas, Enrique, Shearn, Colin, Li, Wei, Stiles, Bangyan L.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Bioenergetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757167/
https://ncbi.nlm.nih.gov/pubmed/23836899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450353
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