Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Signaling Regulates Mitochondrial Biogenesis and Respiration via Estrogen-related Receptor α (ERRα)

Mitochondrial abnormalities are associated with cancer development, yet how oncogenic signals affect mitochondrial functions has not been fully understood. In this study, we investigate the relationship between mitochondrial alterations and PI3K/protein kinase B (AKT) signaling activation using hepa...

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Detalhes bibliográficos
Main Authors: Li, Yang, He, Lina, Zeng, Ni, Sahu, Divya, Cadenas, Enrique, Shearn, Colin, Li, Wei, Stiles, Bangyan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Bioenergetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757167/
https://ncbi.nlm.nih.gov/pubmed/23836899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450353
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