Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Signaling Regulates Mitochondrial Biogenesis and Respiration via Estrogen-related Receptor α (ERRα)

Mitochondrial abnormalities are associated with cancer development, yet how oncogenic signals affect mitochondrial functions has not been fully understood. In this study, we investigate the relationship between mitochondrial alterations and PI3K/protein kinase B (AKT) signaling activation using hepa...

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Detalles Bibliográficos
Main Authors: Li, Yang, He, Lina, Zeng, Ni, Sahu, Divya, Cadenas, Enrique, Shearn, Colin, Li, Wei, Stiles, Bangyan L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Bioenergetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757167/
https://ncbi.nlm.nih.gov/pubmed/23836899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450353
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