Live-Cell Chromosome Dynamics and Outcome of X Chromosome Pairing Events during ES Cell Differentiation

Random X inactivation represents a paradigm for monoallelic gene regulation during early ES cell differentiation. In mice, the choice of X chromosome to inactivate in XX cells is ensured by monoallelic regulation of Xist RNA via its antisense transcription unit Tsix/Xite. Homologous pairing events h...

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Autores principales: Masui, Osamu, Bonnet, Isabelle, Le Baccon, Patricia, Brito, Isabel, Pollex, Tim, Murphy, Niall, Hupé, Philippe, Barillot, Emmanuel, Belmont, Andrew S., Heard, Edith
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756906/
https://ncbi.nlm.nih.gov/pubmed/21529716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.032
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