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Dynamic plasticity of large-scale chromatin structure revealed by self-assembly of engineered chromosome regions

Interphase chromatin compaction well above the 30-nm fiber is well documented, but the structural motifs underlying this level of chromatin folding remain unknown. Taking a reductionist approach, we analyzed in mouse embryonic stem (ES) cells and ES-derived fibroblasts and erythroblasts the folding...

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Detalhes bibliográficos
Main Authors: Sinclair, Paul, Bian, Qian, Plutz, Matt, Heard, Edith, Belmont, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935575/
https://ncbi.nlm.nih.gov/pubmed/20819934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912167
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