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Presynaptic Neurexin-3 Alternative Splicing Trans-Synaptically Controls Postsynaptic AMPA-Receptor Trafficking
Neurexins are essential presynaptic cell-adhesion molecules that are linked to schizophrenia and autism, and are subject to extensive alternative splicing. Here, we used a novel genetic approach to test the physiological significance of neurexin alternative splicing. We generated knock-in mice in wh...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3756801/ https://ncbi.nlm.nih.gov/pubmed/23827676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.060 |
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