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Dissecting the Functions of the Mammalian Clock Protein BMAL1 by Tissue-Specific Rescue in Mice
The bHLH-PAS transcription factor BMAL1 (MOP3) is an essential component of the mammalian circadian pacemaker. Bmal1−/− mice lose circadian rhythmicity but also display tendon calcification and decreased activity, body weight and longevity. To investigate whether these diverse functions of BMAL1 are...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3756687/ https://ncbi.nlm.nih.gov/pubmed/17124323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1132430 |
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