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Synthesis and Biological Activity of 3-N-Substituted Estrogen Derivatives as Breast Cancer Agents

3-N-substituted-estrogen derivatives were synthesized and characterized. Their antiproliferative activities against human ER (+) MCF-7 (Breast), ER (−) MDA-MB-231 (breast) and Ishikawa (endometrial) cancer cell lines were determined after 72 hours drug exposure employing CellTiter-Glo assay at conce...

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Bibliografske podrobnosti
Main Authors: Wan, Zhongliang, Musa, Musiliyu A, Joseph, Patrick, Cooperwood, John S.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756546/
https://ncbi.nlm.nih.gov/pubmed/22876946
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