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Synthesis and antiproliferative activity of coumarin-estrogen conjugates against breast cancer cell lines

The syntheses and cytotoxic activity of coumarin-estrogen conjugates are described. In vitro results indicated that conjugates 10, 11 and 13 show growth inhibitory activities at 5-dose concentration (100, 10, 1, 0.1, 0.01 μM) against the following NCI-7- human breast cancer cell lines: BT-549, HS 57...

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Bibliographic Details
Main Authors: Musa, Musiliyu A., Khan, M. Omar F., Cooperwood, John S.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885731/
https://ncbi.nlm.nih.gov/pubmed/20556210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157018009787582624
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