Geldanamycin-Induced Osteosarcoma Cell Death Is Associated with Hyperacetylation and Loss of Mitochondrial Pool of Heat Shock Protein 60 (Hsp60)

Osteosarcoma is one of the most malignant tumors of childhood and adolescence that is often resistant to standard chemo- and radio-therapy. Geldanamycin and geldanamycin analogs have been recently studied as potential anticancer agents for osteosarcoma treatment. Here, for the first time, we have pr...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gorska, Magdalena, Marino Gammazza, Antonella, Zmijewski, Michal Aleksander, Campanella, Claudia, Cappello, Francesco, Wasiewicz, Tomasz, Kuban-Jankowska, Alicja, Daca, Agnieszka, Sielicka, Alicja, Popowska, Urszula, Knap, Narcyz, Antoniewicz, Jakub, Wakabayashi, Takashi, Wozniak, Michal
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756027/
https://ncbi.nlm.nih.gov/pubmed/24015183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071135
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky