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Activation of Hydrogen Peroxide to Peroxytetradecanoic Acid Is Responsible for Potent Inhibition of Protein Tyrosine Phosphatase CD45

Hydrogen peroxide induces oxidation and consequently inactivation of many protein tyrosine phosphatases. It was found that hydrogen peroxide, in the presence of carboxylic acids, was efficiently activated to form even more potent oxidant - peroxy acid. We have found that peroxytetradecanoic acid dec...

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Main Authors: Kuban-Jankowska, Alicja, Tuszynski, Jack A., Winter, Philip, Gorska, Magdalena, Knap, Narcyz, Wozniak, Michal
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531430/
https://ncbi.nlm.nih.gov/pubmed/23300686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052495
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