No Evidence for Selection of HIV-1 with Enhanced Gag-Protease or Nef Function among Breakthrough Infections in the CAPRISA 004 Tenofovir Microbicide Trial

BACKGROUND: Use of antiretroviral-based microbicides for HIV-1 prophylaxis could introduce a transmission barrier that inadvertently facilitates the selection of fitter viral variants among incident infections. To investigate this, we assessed the in vitro function of gag-protease and nef sequences...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Chopera, Denis R., Mann, Jaclyn K., Mwimanzi, Philip, Omarjee, Saleha, Kuang, Xiaomei T., Ndabambi, Nonkululeko, Goodier, Sarah, Martin, Eric, Naranbhai, Vivek, Karim, Salim Abdool, Karim, Quarraisha Abdool, Brumme, Zabrina L., Ndung'u, Thumbi, Williamson, Carolyn, Brockman, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756015/
https://ncbi.nlm.nih.gov/pubmed/24015191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071758
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky