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Host Targeted Activity of Pyrazinamide in Mycobacterium tuberculosis Infection

Pyrazinamide (PZA) is one of the first line antibiotics used for the treatment of tuberculosis (TB). In the present study, we have used in vitro and in vivo systems to investigate whether PZA, in addition to its known anti-mycobacterial properties, modulate the host immune response during Mycobacter...

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Détails bibliographiques
Auteurs principaux: Manca, Claudia, Koo, Mi-Sun, Peixoto, Blas, Fallows, Dorothy, Kaplan, Gilla, Subbian, Selvakumar
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755974/
https://ncbi.nlm.nih.gov/pubmed/24015316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074082
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