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Host Targeted Activity of Pyrazinamide in Mycobacterium tuberculosis Infection

Pyrazinamide (PZA) is one of the first line antibiotics used for the treatment of tuberculosis (TB). In the present study, we have used in vitro and in vivo systems to investigate whether PZA, in addition to its known anti-mycobacterial properties, modulate the host immune response during Mycobacter...

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Detalhes bibliográficos
Main Authors: Manca, Claudia, Koo, Mi-Sun, Peixoto, Blas, Fallows, Dorothy, Kaplan, Gilla, Subbian, Selvakumar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755974/
https://ncbi.nlm.nih.gov/pubmed/24015316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074082
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