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Mycobacterium leprae alters classical activation of human monocytes in vitro

BACKGROUND: Macrophages play a central role in the pathogenesis of leprosy, caused by Mycobacterium leprae. The polarized clinical presentations in leprosy are associated with differential immune activation. In tuberculoid leprosy, macrophages show a classical activation phenotype (M1), while macrop...

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Bibliografske podrobnosti
izdano v:J Inflamm (Lond)
Main Authors: Fallows, Dorothy, Peixoto, Blas, Kaplan, Gilla, Manca, Claudia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788835/
https://ncbi.nlm.nih.gov/pubmed/26973434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-016-0117-4
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