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Mycobacterium leprae alters classical activation of human monocytes in vitro

BACKGROUND: Macrophages play a central role in the pathogenesis of leprosy, caused by Mycobacterium leprae. The polarized clinical presentations in leprosy are associated with differential immune activation. In tuberculoid leprosy, macrophages show a classical activation phenotype (M1), while macrop...

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Detalles Bibliográficos
Publicado en:J Inflamm (Lond)
Main Authors: Fallows, Dorothy, Peixoto, Blas, Kaplan, Gilla, Manca, Claudia
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788835/
https://ncbi.nlm.nih.gov/pubmed/26973434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-016-0117-4
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