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Physiologically based pharmacokinetic modeling of arterial – antecubital vein concentration difference

BACKGROUND: Modeling of pharmacokinetic parameters and pharmacodynamic actions requires knowledge of the arterial blood concentration. In most cases, experimental measurements are only available for a peripheral vein (usually antecubital) whose concentration may differ significantly from both arteri...

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Bibliografische gegevens
Hoofdauteur: Levitt, David G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC375538/
https://ncbi.nlm.nih.gov/pubmed/15053829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-4-2
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