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Physiologically based pharmacokinetic modeling of arterial – antecubital vein concentration difference
BACKGROUND: Modeling of pharmacokinetic parameters and pharmacodynamic actions requires knowledge of the arterial blood concentration. In most cases, experimental measurements are only available for a peripheral vein (usually antecubital) whose concentration may differ significantly from both arteri...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC375538/ https://ncbi.nlm.nih.gov/pubmed/15053829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-4-2 |
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