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PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol
BACKGROUND: A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific solutes, required specification of a large number of parameters and have not been designed for general...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126244/ https://ncbi.nlm.nih.gov/pubmed/12182760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-2-5 |
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