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PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol

BACKGROUND: A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific solutes, required specification of a large number of parameters and have not been designed for general...

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Библиографические подробности
Главный автор: Levitt, David G
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2002
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC126244/
https://ncbi.nlm.nih.gov/pubmed/12182760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-2-5
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