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Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines

Hepatitis C virus (HCV) remains a major medical problem. In-depth study of HCV pathogenesis and immune responses is hampered by the lack of suitable small animal models. The narrow host range of HCV remains incompletely understood. We demonstrate that the entire HCV life-cycle can be recapitulated i...

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Detalhes bibliográficos
Main Authors: Vogt, Alexander, Scull, Margaret A., Friling, Tamar, Horwitz, Joshua A., Donovan, Bridget M., Dorner, Marcus, Gerold, Gisa, Labitt, Rachael N., Rice, Charles M., Ploss, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755106/
https://ncbi.nlm.nih.gov/pubmed/23777661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.05.036
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