Fatty acid synthesis is a therapeutic target in human liposarcoma

Liposarcomas (LS) are mesenchymal tumors that can recur after surgical resection and often do not respond to presently available medical therapies. This study demonstrates the dependence of LS on de novo long-chain fatty acid synthesis for growth. Lipogenesis can be impaired by inhibiting the activi...

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Main Authors: Olsen, Arne M., Eisenberg, Burton L., Kuemmerle, Nancy B., Flanagan, Alison J., Morganelli, Peter M., Lombardo, Portia S., Swinnen, Johannes V., Kinlaw, William B.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754849/
https://ncbi.nlm.nih.gov/pubmed/20372807
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