Conjugated Linoleic Acid (CLA) inhibits expression of the Spot 14 (THRSP) and fatty acid synthase genes and impairs the growth of human breast cancer and liposarcoma cells

Spot 14 (THRSP, S14) is a nuclear protein involved in the regulation of genes required for fatty acid synthesis in normal and malignant mammary epithelial and adipose cells. Havartine and Bauman reported that conjugated linoleic acid (CLA) inhibits S14 gene expression in bovine mammary and mouse adi...

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Bibliographic Details
Main Authors: Donnelly, Christina, Olsen, Arne M., Lewis, Lionel D., Eisenberg, Burton L., Eastman, Alan, Kinlaw, William B.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872989/
https://ncbi.nlm.nih.gov/pubmed/19116881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635580802348666
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