Lipoprotein lipase links dietary fat to solid tumor cell proliferation

Many types of cancer cells require a supply of fatty acids (FA) for growth and survival, and interrupting de novo FA synthesis in model systems causes potent anticancer effects. We hypothesized that, in addition to synthesis, cancer cells may obtain pre-formed, diet-derived fatty acids by uptake fro...

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Главные авторы: Kuemmerle, Nancy B., Rysman, Evelien, Lombardo, Portia S., Flanagan, Alison J., Lipe, Brea C., Wells, Wendy A., Pettus, Jason R., Froehlich, Heather M., Memoli, Vincent A., Morganelli, Peter M., Swinnen, Johannes V., Timmerman, Luika A., Chaychi, Leila, Fricano, Catherine J., Eisenberg, Burton L., Coleman, William B., Kinlaw, William B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074101/
https://ncbi.nlm.nih.gov/pubmed/21282354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0802
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