Lipoprotein lipase links dietary fat to solid tumor cell proliferation

Many types of cancer cells require a supply of fatty acids (FA) for growth and survival, and interrupting de novo FA synthesis in model systems causes potent anticancer effects. We hypothesized that, in addition to synthesis, cancer cells may obtain pre-formed, diet-derived fatty acids by uptake fro...

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Hauptverfasser: Kuemmerle, Nancy B., Rysman, Evelien, Lombardo, Portia S., Flanagan, Alison J., Lipe, Brea C., Wells, Wendy A., Pettus, Jason R., Froehlich, Heather M., Memoli, Vincent A., Morganelli, Peter M., Swinnen, Johannes V., Timmerman, Luika A., Chaychi, Leila, Fricano, Catherine J., Eisenberg, Burton L., Coleman, William B., Kinlaw, William B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074101/
https://ncbi.nlm.nih.gov/pubmed/21282354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0802
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