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Rescued Tolerant CD8 T Cells Are Preprogrammed to Reestablish the Tolerant State
Tolerant self-antigen–specific CD8 T cells fail to proliferate in response to antigen, thereby preventing autoimmune disease. By using an in vivo mouse model, we show that tolerant T cells proliferate and become functional under lymphopenic conditions, even in a tolerogenic environment. However, T c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754789/ https://ncbi.nlm.nih.gov/pubmed/22267581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1214277 |
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