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SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells
During responses against viruses and malignancies, naïve CD8 T lymphocytes expand to form both short-lived effector cells (SLECs) and a population containing cells with the potential to be long-lived and participate in memory responses (MPECs). The strength of antigenic, costimulatory, and cytokine...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980864/ https://ncbi.nlm.nih.gov/pubmed/20696858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001362 |
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