Restoration of CD28 Expression in CD28(−) CD8(+) Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production

The control of many persistent viral infections by Ag-specific cytolytic CD8(+) T cells requires a concurrent virus-specific CD4(+) Th cell response. This reflects in part a requirement of activated effector CD8(+) T cells for paracrine IL-2 production as a growth and survival factor. In human CMV a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Topp, Max S., Riddell, Stanley R., Akatsuka, Yoshiki, Jensen, Michael C., Blattman, Joseph N., Greenberg, Philip D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2003
Pynciau:
Brief Definitive Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194206/
https://ncbi.nlm.nih.gov/pubmed/12963692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021288
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