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Control of Memory CD8(+) T Cell Differentiation by CD80/CD86-CD28 Costimulation and Restoration by IL-2 during the Recall Response
Memory CD8(+) T cell responses have been considered to be independent of CD80/CD86-CD28 costimulation. However, recall responses are often severely blunted in CD28(−/−) mice. Whether this impairment represents a requirement for CD28 costimulation for proper memory CD8(+) T cell development or a requ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954438/ https://ncbi.nlm.nih.gov/pubmed/18178855 |
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