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Differential requirement for CD28 and CD80/86 pathways of costimulation in the long-term control of murine gammaherpesvirus-68.
The costimulatory molecules CD80 and CD86 (B7-1 and B7-2) are upregulated on mature antigen-presenting cells and interact with positive and negative regulators of CD8 T cell function, CD28 and CD152 (CTLA4) respectively. In this study we examined the role of CD80 and CD86 in the immune response to m...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847573/ https://ncbi.nlm.nih.gov/pubmed/16934307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.06.039 |
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