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Recall responses by helpless memory CD8+ T cells are restricted by the upregulation of PD-1

CD4 help is crucial for memory CD8+ T cell development; yet the mechanisms of CD4 help and why (CD4) helpless memory CD8+ T cells elicit poor recall responses are currently not well understood. In this study we investigated these questions using an in vivo acute virus infection model. We show here t...

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Sonraí Bibleagrafaíochta
Main Authors: Fuse, Shinichiro, Tsai, Ching-Yi, Molloy, Michael J., Allie, S. Rameeza, Zhang, Weijun, Yagita, Hideo, Usherwood, Edward J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713929/
https://ncbi.nlm.nih.gov/pubmed/19299723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802041
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