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Recall responses by helpless memory CD8+ T cells are restricted by the upregulation of PD-1
CD4 help is crucial for memory CD8+ T cell development; yet the mechanisms of CD4 help and why (CD4) helpless memory CD8+ T cells elicit poor recall responses are currently not well understood. In this study we investigated these questions using an in vivo acute virus infection model. We show here t...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713929/ https://ncbi.nlm.nih.gov/pubmed/19299723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802041 |
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