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Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells
The transcription factor Runx1 is essential for the formation of yolk sac-derived erythroid/myeloid progenitors (EMPs) and hematopoietic stem cells (HSCs) from hemogenic endothelium during embryogenesis. However, long-term repopulating HSCs (LT-HSCs) persist when Runx1 is conditionally deleted in fe...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Company of Biologists
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754475/ https://ncbi.nlm.nih.gov/pubmed/23924635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.094961 |
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