Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells

Hematopoietic stem cells (HSC) and an earlier wave of definitive erythroid/myeloid progenitors (EMPs) differentiate from hemogenic endothelial cells in the conceptus. EMPs can be generated in vitro from embryonic or induced pluripotent stem cells, but efforts to produce HSCs have largely failed. The...

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Autores principales: Chen, Michael J., Li, Yan, De Obaldia, Maria Elena, Yang, Qi, Yzaguirre, Amanda D., Yamada-Inagawa, Tomoko, Vink, Chris S., Bhandoola, Avinash, Dzierzak, Elaine, Speck, Nancy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576591/
https://ncbi.nlm.nih.gov/pubmed/22136929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.10.003
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