Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells

Hematopoietic stem cells (HSC) and an earlier wave of definitive erythroid/myeloid progenitors (EMPs) differentiate from hemogenic endothelial cells in the conceptus. EMPs can be generated in vitro from embryonic or induced pluripotent stem cells, but efforts to produce HSCs have largely failed. The...

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Detalhes bibliográficos
Main Authors: Chen, Michael J., Li, Yan, De Obaldia, Maria Elena, Yang, Qi, Yzaguirre, Amanda D., Yamada-Inagawa, Tomoko, Vink, Chris S., Bhandoola, Avinash, Dzierzak, Elaine, Speck, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576591/
https://ncbi.nlm.nih.gov/pubmed/22136929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.10.003
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