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Phase I, Open-Label, Single-Dose Study To Evaluate the Pharmacokinetics and Safety of Telbivudine in Children and Adolescents with Chronic Hepatitis B

Telbivudine is a nucleoside analogue that has been approved for the treatment of chronic hepatitis B virus (HBV) infection in adults at 600 mg/day. We conducted a phase I, open-label, first-in-pediatrics study to investigate the safety and pharmacokinetics of a single dose of telbivudine in HBV-infe...

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Detalhes bibliográficos
Main Authors: Stein, Daniel S., Ke, June, Uy, Grace, Bosheva, Miroslava, Qi, Yin, Praestgaard, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754306/
https://ncbi.nlm.nih.gov/pubmed/23774433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00117-13
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