An Open-Label Study of the Impact of Hepatic Impairment on the Pharmacokinetics and Safety of Single Oral and Intravenous Doses of Omadacycline

Omadacycline is a once-daily oral or intravenous (i.v.) aminomethylcycline antibiotic approved in the United States for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) in adults. Omadacycline pharmacokinetics were charact...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Kovacs, Steven J., Ting, Lillian, Praestgaard, Jens, Sunkara, Gangadhar, Sun, Haiying, Stein, Daniel S., Tanaka, S. Ken, Villano, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577144/
https://ncbi.nlm.nih.gov/pubmed/32839218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01650-20
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