The BpeEF-OprC Efflux Pump Is Responsible for Widespread Trimethoprim Resistance in Clinical and Environmental Burkholderia pseudomallei Isolates

Trimethoprim-sulfamethoxazole (co-trimoxazole) is the primary drug used for oral eradication therapy of Burkholderia pseudomallei infections (melioidosis). Here, we demonstrate that trimethoprim resistance is widespread in clinical and environmental isolates from northeast Thailand and northern Aust...

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Detalhes bibliográficos
Main Authors: Podnecky, Nicole L., Wuthiekanun, Vanaporn, Peacock, Sharon J., Schweizer, Herbert P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754293/
https://ncbi.nlm.nih.gov/pubmed/23817379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00660-13
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