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Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells
RUNX1 is generally considered a tumor suppressor in myeloid neoplasms. Inactivating RUNX1 mutations have frequently been found in patients with myelodysplastic syndrome (MDS) and cytogenetically normal acute myeloid leukemia (AML). However, no somatic RUNX1 alteration was found in AMLs with leukemog...
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Main Authors: | , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754260/ https://ncbi.nlm.nih.gov/pubmed/23979164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68557 |
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